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After intravenous administration of fluorescein, enhancement of the gaps between epithelial cells (1), leakage of fluorescein into the bowel lumen (2), and cell shedding (3) can be directly visualized using a confocal probe equipped with a 488 nm laser ( ex vivo permeability ( Finally, mucosal impedance testing is another tool to directly evaluate mucosal integrity, although most studies are limited to the esophagus

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The assignment of 6.12 achievement points under the proposed administrative claims-based quality measure scoring methodology would be closer to the performance threshold equivalent of 7.5 than the assignment of 2.83 achievement points under the current scoring methodology, as discussed in our previous example in section IV.B.1.a.(2)(b)(i) of this final rule