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473 For example, the intestinal commensal fungus Kazachstania pintolopesii secretes a 12-amino-acid peptide fragment of Ygp1 that suppresses epithelial apoptosis and inflammatory responses in the colon

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Previous studies showed that a Th2 response mostly induce ADA production of the IgG4 isotype, in comparison to the Th1 response, that in the case of anti-factor VIII elicits the generation of IgG1 and IgG2 ADA (58, 59)