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In the inflamed tissue microenvironment of IBD patients, infiltrating immune cells, together with the energy requirements of resident epithelial and stroma cells limit the available oxygen 14 , and together with a reduced blood supply, these changes contribute to hypoxic conditions in chronic inflammation 15

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Unlike other GHRPs, Ipamorelin does not affect the release of cortisol, acetylcholine, prolactin, or aldosterone, thus minimizing the adverse side effects of other growth hormone therapies, such as increased hunger