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CAFs can be reprogrammed toward a glycolytic phenotype in breast and head/neck carcinomas in a process called “reverse Warburg” metabolism, so-named because of its implication that aerobic glycolysis can take place in the tumor-associated stroma and not only epithelial tumor cells (reviewed in [69, 135•, 157, 158])

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Nov 1 2005;23(31):7974-7984