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In ALs and CALs, OPCs downregulate pathways linked to cholesterol homeostasis, peroxisome function, Myc, mTORC1, oxidative phosphorylation, and IFNγ signaling, suggesting a reduced metabolic and biosynthetic state that may reflect quiescence or a protective adaptation to inflammation

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22 Another report demonstrates a case of bilateral central serous chorioretinopathy following excessive daily consumption of DIM for two months