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intracellular proteins, such as phosphoinositide 3 kinase (PI3K), MEK, RalA GTPase, GRK interacting protein-1 (GIT-1) and adenomatous polyposis coli (APC) protein
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The sarcoplasmic protein can then be filtered in the glomerulus and accumulates in the tubules, thus causing acute renal failure and other life-threatening complications, such as hyperkalemia and cardiac arrhythmias [142,143]
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