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Increased risk of diarrhea-predominant irritable bowel syndrome (IBS-D) Increased insulin resistance and glucose intolerance, contributing to elevated blood glucose Poor wound healing, altered taste and smell, and changes in cognitive function, particularly in older adults How common is zinc deficiency

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Monitoring Protocol: Although the trials showed no concerning laboratory changes, prudent clinical practice suggests baseline and periodic monitoring of metabolic parameters, complete blood counts, liver function, and kidney function