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Following this, there have been two clinical phase 2 trials (SAR425899 and MEDI0382 also known as cotadutide) published evaluating GLP-1/glucagon receptor co-agonists
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In addition, the necroptosis inhibitor necrostatin-1 has off-target activity, which can suppress ferroptosis at high concentrations (Friedmann Angeli et al., 2014), but this is unrelated to necroptosis
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