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Other studies that assessed cortical GSH levels by proton magnetic resonance spectroscopy suggested that GSH may be a biomarker of depression, with lower levels in patients with major depression ( Other biological processes beyond oxidative stress and antioxidant function are related to mental disorders, such as inflammation, which can reduce the biosynthesis and availability of neurotransmitters and affect neuroplasticity (Sperner-Unterweger et al., 2014