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Certain inflammation-related factors, such as lipopolysaccharides, can activate Piezo1 channels, triggering both the influx of calcium ions and also the release of intracellular stores of calcium ions, leading to oxidative cellular damage and disintegration of the CNS cytoskeleton, manifesting as irreversible neurodegeneration (Arishe et al., 2020

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I like to give the kelp because it seems to work (I don't really know...but it seems to help) and it shouldn't hurt if they don't need it