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Before performing the definitive graft on hypopigmented patches that have been stable for at least two years, it is strongly advised to perform a mini-grafting test to evaluate the patient's positive response and the unfavorable occurrence of Koebner's phenomenon at the donor site after two to three months of follow-up

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For example, biomarker expression characteristics of a sample derived from a non-cancerous tissue of a subject and/or characteristics generated from a population-based distribution of informative loci of interest in a relevant population of the same species may be stored and later compared to a sample derived from a cancerous tissue of a subject or a suspected cancerous tissue of a subject