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Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells | Cell Death & Disease

BPC-157 is a pentadecapeptide derived from the stomach that operates via an intricate network of cytoprotection and angiogenesis mechanisms, including VEGFR2, NO-eNOS signaling, FAK-paxillin interaction and others, with its most solid data being derived from gastrointestinal, tendon, ligament, bone, and increasingly neural studies

tissue regeneration

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This work underscores the critical need to address the growing global prevalence of neurodegenerative diseases by advancing our understanding of the gut–brain axis