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The MTHFR C677T polymorphism was shown to be associated with inflammatory diseases, such as psoriasis (Caucasian Czech population) [31] and inflammatory bowel disease (Caucasian Irish population) [32], while both C677T and A1298C variants have been linked to rheumatoid arthritis in a Caucasian and Asian population [33,34]

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doi: 10.1080/03602532.2017.1306544