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10.1055/s-0044-1786397 [DOI] [PubMed] [Google Scholar] 166

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A hallmark of SIOP is a reduction in osteoblast numbers ( c − ( Obesity-related osteoporosis Obesity causes adipocyte accumulation in bone marrow, which leads to osteoprogenitor cell dysfunction in aging ( Hereditary hemochromatosis and osteoporosis Beyond metabolic disorders such as diabetes mellitus and obesity, genetically determined diseases characterized by systemic iron overload may provide further insight into the role of ferroptosis in bone pathology