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Research reported mean on-treatment weight reduction of 22.7% with CagriSema at 68 weeks, versus 16.1% for semaglutide alone, 11.8% for cagrilintide alone, and 2.3% for placebo — among the highest weight-outcome magnitudes reported for any anti-obesity intervention to date, alongside improvements in blood pressure, waist circumference, lipid measures, and glycemic parameters 3