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And there are some conditions where they may provide small or no improvement.” The global peptide-therapeutics market has swelled to over $50 billion in annual sales and is projected to nearly double again in roughly the next decade

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Indeed, it was recently demonstrated that the pentose phosphate pathway (PPP), a major contributor of NADPH for the maintenance of glutathione in its reduced state, is critical for NRF2-induced proliferation [58, 59]