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This complex communication network, known as the GBA, comprises a vast number of mechanisms and elements such as the hypothalamic-pituitary-adrenal (HPA) axis, which is a fundamental component in how the body responds to stressful stimuli, immune cells, such as cytokines and chemokines, the vagus nerve, which is primarily involved in the mind-body connection, short-chain fatty acids (butyrate), neurotransmitters, and neuropeptides like serotonin (5-HT), GABA, dopamine, leptin, melatonin, histamine, and acetylcholine [34]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 213.Tóth S.Z., Puthur J.T., Nagy V., Garab G