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Estimated plasma half-life is approximately 2 hours, though precise human pharmacokinetic data remain limited and are largely extrapolated from animal and in vitro systems
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79 Just as reduction followed by glycosylation inactivates juglone, deglycosylation of HJG by an unknown β-glucosidase purified from English walnut husks releases hydrojuglone aglycone, which then spontaneously oxidizes to generate active juglone
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