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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Yang W-H, Ding C-KC, Sun T, Rupprecht G, Lin C-C, Hsu D, and Chi J-T (2019)

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M1 phenotype macrophages are tumor-resistant and can enhance anti-tumor inflammatory reactions, while the M2 phenotype has tumor-promoting capabilities involving angiogenesis, immunosuppression, and neovascularization, as well as stromal activation and remodeling (Wagner et al., 2012)