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Human AEC (hAEC) exerted an inhibitor effect on proliferation of naive CD4 + T cells and production of Th1 and Th17 cytokines, while induced production of Th2 cytokines and augmented differentiation of Tregs and production of TGF-β1 and IL-10 ( There is an increasing body of evidence suggesting a noticeable link between a pro-senescent decidual response in peri-implantation endometrium and recurrent pregnancy loss ( In the past decade, exosomes have emerged as novel mediators of intercellular communication by transfer of signaling molecules ( in vitro and in vivo and have diverse functions such as apoptosis induction and cytotoxicity reduction ( Although, with a default conception in mind of the immunoregulatory activity of trophoblasts, most researchers have come to the conclusion that these cells exert suppressive activity on the uterine immune system, interpretation of these results should be made with caution

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biochemical detection for lipid profiles