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Causes and Risk Factors of Peripheral Neuropathy The nerve damage behind neuropathy can happen in a variety of ways, affecting the nerve axons (along which impulses transmit to other cells), myelin sheath (which covers and protects the axon), or a combination of both

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Inducible piSMART shRNA plasmids (V3SM11253-231787949 for the shGrpr and VSC11655 for the non-targeting shRNA, Dharmacon) were infected in 1057 melanoma cells, and positive cells were selected using 1.2 µg ml −1 puromycin