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One type of MDR is based on overexpression of efflux pumps at the plasma membrane, such as P-gp, MRP1, and BCRP, resulting in strongly reduced intracellular drug concentrations [12]

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In younger individuals, supplementing with this bioactive amino complex takes a proactive approach, while replenishing levels in individuals with age-induced declines and/or increased regenerative or oxidative stress requirements provides support in targeted applications