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32,47 The key factors increasing β cell death include endoplasmic reticulum stress (leading to accumulation of unfolded and misfolded proteins within this key subcellular compartment critical in the biosynthesis of secretory and structural proteins as well as steroids, cholesterol, and other lipids), oxidative stress, mitochondrial dysfunction, inflammatory stress, and inclusions of aggregated peptides that reside within a similar intracellular milieu as do neuronal cells in PD

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HSA and FSA funds can be applied to physician-prescribed peptide therapy when medical necessity is documented, and initial lab work is frequently covered even when the therapy itself is not