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The vulnerability of a recipient to fungal infection is governed by several contributors, mainly immune flaws caused by underlying disorders necessitating an organ transplant (167, 168), organ transplanted type, complications associated with surgery (152, 160, 167), metabolic changes, net state of immunosuppression, infections by viruses, loss of renal function and supplementary therapy to manage graft rejection (152, 165, 169)

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Strikingly, a visual examination of available HSAN1 patients demonstrated that most could also be diagnosed with MacTel, in particular, some cases with early-onset macular and visual defects (35)