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In both human AD brains and mouse models, markers of ferroptosis—such as iron accumulation, glutamate excitotoxicity, and lipid ROS buildup—are frequently observed (288)
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Drug concentrations required to reduce viral cytopathic effect by 50% (EC50) were calculated using nonlinear regression from plots of percentage cell viability versus log 10 drug concentration using GraphPad Prism v.9.5.1 (GraphPad Software)
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