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Another study on the effect of Xn-loaded PLGA NPs on melanoma shows a statistically significant difference and improvement in XN-induced polarization with anti-inflammatory activities in CD86, a type 1 membrane immunoglobulin expressed in B cells and macrophages (Fonseca et al., 2021)

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MPTP and its active metabolite MPP + have been widely used in experimental animals and cell models of PD, respectively