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Intravenous administration in mice showed that NRH is more potent at raising NAD + levels in the liver and muscle than NR and NMN 128

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In one approach, the transduction of an adeno-associated vector serotype 8 (AAV8) encoding the human ATP7B cDNA placed under control of the liver specific α1-antitrypsin promoter allowed long-term correction of copper metabolism in Atp7b null mice (92,93)

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