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For example, M1 polarization is associated with the stimulation of pro-inflammatory cytokines such as TNF-α, IL-1, IL-6, and IL-12 and the activation of the transcription factors STAT1 and NF-κB ( Targeting specific pathways and transcription factors may prove beneficial in promoting the desired M2 polarization state

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Athletes and individuals with demanding lifestyles can particularly benefit from this boost in cellular energy