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ACh is synthesized from choline and acetyl-CoA by choline acetyltransferase (ChAT) at presynaptic terminals and exerts a wide range of physiological effects, including vasodilation, stimulation of gastrointestinal peristalsis, modulation of bladder function, and contributions to muscle contraction, immune regulation, and cognitive function [101]

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Oprocz badan komorkowych i genowych istnieje szereg badan miejscowych i klinicznych, ktore w pracach przegladowych podsumowywane sa neutralnie