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Topoisomerase inhibitors: Camptotheca (Camptothecin, Topotecan, Irinotecan, Rubitecan, Belotecan), Podophyllum (Etoposide, Teniposide)
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In a 6-hydroxydopamine (6-OHDA)-induced PD model, it reduces ROS levels and activates antioxidant pathways to inhibit ferroptosis, protecting dopaminergic neurons (Chen QX
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