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A sufficiently profitable method, with the maximum specified therapeutic effect, could be the use of low or medium doses of single strains of probiotics, with the selection of the desired strains, and then a special phase that cannot be avoided: “personalized” to the sensitivity of the strain

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This integrative approach will facilitate the characterization of disease-specific epigenetic and metabolomic profiles, supporting the development of personalized, mechanism-based therapeutic strategies in autoimmune conditions