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Biesiekierski JR, Peters SL, Newnham ED, et al
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Hence, the inactivation or loss of GPX4 due to genetic inhibition or inhibitors or GSH depletion could result in L-OOH accumulation, triggering ferroptotic cell death ( 2.2 The iron metabolism axis Iron is an essential trace element in the human body, mainly in the form of divalent iron (Fe 2+ ) and trivalent iron (Fe 3+ )
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