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The inflammatory response involves a variety of cytokines, chemokines, and proteins that directly or indirectly induce IκB kinase-β (IκKβ), JNK, or signal transducer and activator of transcription (STAT) signaling cascades

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Polyamine metabolism and necroptosis associate with increased survival of humans with cancer To identify links between polyamine metabolism, necroptosis, and cancer prognosis, we analyzed survival data from patients with cancer, stratified by the expression levels of necroptosis-related molecules RIPK3 and MLKL, and enzymes involved in polyamine metabolism