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When used to treat wounds, researchers observed that hair follicles surrounding treated areas appeared notably enlarged, suggesting GHK-Cu plays a role in preventing follicular miniaturization and potentially increasing follicle size

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Overall, commenters stated that, adopting these changes would align with the intent of the NO PAIN Act (section 4135 of the Consolidated Appropriations Act (CAA), 2023) and CMS' recognition of cryoablation devices in recent payment rules, ultimately accelerating adoption of evidence-based, non-opioid pain management strategies while supporting innovation in patient care