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These antioxidant molecules react and scavenge the atomically unstable molecules, protecting the intracellular redox milieu
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Cells lacking merlin also show elevated levels of several other RTKs, including IGF-1R, MET, and the EGFR family members ErbB2 and ErbB3 ( Additionally, merlin suppresses the Hippo/ la rge t umor s uppressor kinase 1/2 (LATS1/2)/Yes-associated protein (YAP) pathway ( DCAF1 in the nucleus ( via inhibition of the eIF4E-binding protein (4E-BP) ( NF2 -deficient cells also display mTORC2 activation
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