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Kelp lab · Specimen ledger
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Description
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Leucine sensing: Similar to the CASTOR proteins in arginine sensing, SESTRIN proteins bind and inactivate GATOR2 in leucine-deprived cells (Chantranupong et al., 2014
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A SNP on ALPL is associated with faster clearance of vitamin B6 (hence lower B6 status) and potentially lower GABA levels
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