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doi: 10.1007/s00330-015-3696-1 [DOI] [PMC free article] [PubMed] [Google Scholar] 260.Daulatzai MA

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It competitively binds p53, displacing endogenous FOXO4 in senescent cells (Baar et al., 2017) 24-72 hours: Freed p53 translocates to mitochondria in senescent cells, triggering the intrinsic apoptotic cascade