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In these very early stages of gamete formation, several genes and transcription factors are important: SOX17, PRDM1, PRDM14, transcription factor AP-2 gamma, involved in upregulating germ cells and inhibiting somatic markers [8], STAG3, involved in chromosome segregation, and BUB1B, responsible for the formation of mitotic checkpoint serine/threonine kinase B [7], playing an important role in the kinetochore formation and dynamics [8]

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