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Adults (19-64 years) are usually recommended to consume about 1.5 micrograms a day or more if they are not getting sufficient B12 from their diets

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References Primary sources for this guide: PMID 39161060 (Diabetes, Obesity and Metabolism, 2024) for the mouse pharmacokinetics by intravenous, subcutaneous and oral routes, the 3.5% oral bioavailability, the 78 ng/mL mouse NNMT IC50, the hepatocyte stability data and the 28–30 day efficacy study