Lab notes
Wave shelves · perforated field sheets
Description
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gingivalis LPS) significantly downregulated both the transcription and protein expression of SLC7A11 via the TLR4/NF-κB pathway, inhibiting cystine uptake, leading to insufficient GSH synthesis and loss of GPX4 activity (40), thereby directly impairing cellular antioxidant capacity
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Although a substantial amount of knowledge has been generated regarding the mechanism of action of both drug classes, much remains to be understood
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