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MorgensternYLeeJNaYGwynneWHurrenRMaLet alAML Drug tolerant persister (DTP) cells survive chemotherapy by transiently altering cellular lipidomics to increase plasma membrane rigidity, but also increases sensitivity to immune cell killing

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Considering absolute production within the three organelles and their relative permeability for ROS (Table 1), the ER emerges as the relative most important contributor to cytosolic ROS amounts from purified organelles with approximately 60% of ROS derived from this organelle, and the remainder evenly split between mitochondria and peroxisomes 45