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α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitors ACMSD plays a crucial role in the kynurenine pathway, serving as a branching point between NAD + and acetyl-CoA production 234

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Another study revealed a significant reduction in sperm kinetic parameters and a decrease in the percentage of normal sperm morphology of male diabetic partners (147)