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The introduction of the third arginine disrupted the binding site between natural IGF-1 and IGFBP-3, increasing the free concentration of IGF-1 LR3 by about 10 times
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Looking at the body’s homeostasis as a whole, Cu is involved in several reactions as a component of the following enzymes: SOD, COX, diamine oxidase (DAO), and skin lysis oxidase (SLO) [102]
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