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Genetics and Stability While many Canadian parents notice their newborns’ eyes shifting from blue to brown or grey in the first year of life, this is due to the slow maturation of melanocytes (melanin-producing cells)

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At this point further modifications catalyzed by aldehyde dehydrogenase and aldo-keto reductase allow to obtain carboxyethylmercapturic acid and 3-hydroxypropylmercapturic acid respectively, which are escreted with urine (Fig