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P W Mahasha reports support for attending meetings and/or travel from the South African Medical Research Council, Department of Nuclear Medicine, School of Medicine, University of Pretoria, Discipline of Traditional Medicine, School of Nursing and Public Health, University of KwaZulu Natal

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The most frequently reported adverse effects in clinical trials were gastrointestinal in nature, reflecting tirzepatide's mechanism of action as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist