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Schisandrin B prevented cyclosporine A-induced oxidative stress in human immortalized proximal tubular epithelial HK-2 cells and protected human keratinocyte-derived HacaT cells against t-butyl hydroperoxide-induced oxidative stress via scavenging ROS, increasing levels of mitochondrial membrane potential and GSH, promoting Nrf2 translocation into the nucleus followed by the target gene expression [48,49]

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Superoxide dismutase, or SOD, is a naturally occurring enzyme that helps neutralize free radicals produced during normal metabolic processes