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Ferroptosis inhibitors like Fer-1 and Liproxstatin-1 (Lip-1) effectively reduce the accumulation of Lipid-ROS, thereby inhibiting chondrocyte ferroptosis and delaying OA progression (Skouta et al., 2014

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Quercetin, a widely distributed flavonoid, significantly suppresses ferroptosis through the activation of the Nrf2 protein (258)