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The outcomes of clinical studies dealing with an association between the use of PPIs and the risk of dementia and AD are heterogenous, as reviewed in a recent meta-analysis involving ten independent studies with more than 600,000 patients [224]

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Samples for the quantification of formate by HPLC were generated by centrifugation of 500 µL of cell culture at 11,000 x g, 4 °C for 3 min