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For CLL patients on newer agents (e.g., ibrutinib) which are once-daily, timing at Iftar is convenient

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Liraglutide (Saxenda) has a separate NICE appraisal (TA664) with more specific eligibility criteria: BMI ≥35 kg/m² (or ethnicity-adjusted equivalent) with non-diabetic hyperglycaemia (pre-diabetes) and high cardiovascular risk Must be used within a specialist weight management service Similar ethnicity-adjusted BMI thresholds apply as for semaglutide A 12-week assessment at the 3 mg dose is recommended