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It is noteworthy that while the development of new knockout mice no longer appears on the cover of major journals nearly every other month, the remaining importance and underlying need to generate/distribute new knockout lines of mice are highlighted by the creation of investigator-driven consortiums (see for example, the goals of which are to generate null alleles (i.e., knockout mice) for every gene of the mouse genome (reviewed in Rosenthal 2007)

180 days

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